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分析基因表达图式的新方法
Novel Methods of Gene Expression Pattern Analysis.
【摘要】 随着基因组研究的深入进行,基因的分子生物学除了要寻找在生物学上重要的个别基因并研究其结构与功能外,更重要的应是了解整个基因组的功能活动,即细胞全部基因的表达图式.要解决如此复杂的问题就必须在研究方法上有所创新,基因表达系列分析法、cDNA微阵列分析法、DNA微芯片分析法等正是近几年发展起来的分析基因表达图式的新方法
【Abstract】 In the progress of the genome projects, the most important purpose of molecular biology of the gene is to investigate the structure and function of not only single important gene but also the whole genome, that is the gene transcription and expression patterns of the whole cell. In order to resolve such complex problem, revolutionary research methods must be developed. Serial analysis of gene expression(SAGE), cDNA microarray, DNA microchip are the novel methods for fast and quantitative analysis of gene characteristics which are recently advanced in this background.
【Key words】 gene expression patterns; serial analysis of gene expression (SAGE); cDNA microarray; DNA microchip;
- 【文献出处】 生物化学与生物物理进展 ,PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS , 编辑部邮箱 ,1999年02期
- 【分类号】Q523.8
- 【被引频次】9
- 【下载频次】143