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干燥综合征动物模型的建立及中药疗效的观察

Exprimental research on animal model and treatment of Sjgrens syndrome by traditional chinese medicine(TCM)

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【作者】 俞创奇邱蔚六胡北平丁永敏

【Author】 Yu Chuangqi,Qiu Weiliu,Hu Beiping,et al. Department of Oral and Maxillofacial Surgery,School of Stomatology,Shanghai Second Medical University,Shanghai 200011

【机构】 上海第二医科大学口腔医学院口腔颌面外科教研室

【摘要】 目的进一步确立干燥综合征(SS)的动物模型并观察中药制剂SS糖浆治疗干燥综合征的疗效。方法采用利血平+甲状腺素造型法的气阴二虚证动物模型,应用SS糖浆进行疗效的观察。结果SS糖浆治疗组各项观察指标有明显改善,动物体重增加情况、饮水量及cAMP值均接近正常对照组(P>0.05)。而实验对照组和治疗对照组无明显变化(P<0.05)。结论进一步明确了SS糖浆具有一定的健脾益气,滋阴润燥功能,为临床推广应用提供了依据

【Abstract】 Objective To confirm the function of SS Syrup used in our department. Methods Under the basis of TCM and differentiation symptoms of SS,the animal model was established and applied to test the function of SS syrup.There are three indices to be observed,weight change,volume of drinking water daily,cAMP change. Results The three observed indices of deficiency symptom model had been rectified by SS syrup. Conclusion SS syrup has two main functions:(1)reinforcing of the spleen and tonifying qi;(2)nourishing liver yin and kidney yin as well as removing pathogenic heat and fire.

  • 【文献出处】 上海口腔医学 ,SHANGHAI JOURNAL OF STOMATOLOGY , 编辑部邮箱 ,1999年01期
  • 【分类号】R259.932
  • 【被引频次】19
  • 【下载频次】296
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