【摘要】 目的对百合科（Ｌｉｌｉａｃｅａｅ）植物卷叶贝母（ＦｒｉｔｉｌｌａｒｉａｃｉｒｒｈｏｓａＤ．Ｄｏｎ）的干燥鳞茎进行化学成分研究。方法通过提取和层析进行成分分离，运用化学和现代光谱手段进行结构鉴定。结果从中分得３个化合物，分别鉴定为（２２Ｒ，２５Ｓ）－ｓｏｌａｎｉｄａｎｅ－３β－醇（Ⅰ）、胸苷（Ⅱ）和腺苷（Ⅲ）。结论化合物Ⅰ为首次从贝母属植物中分得，腺苷具有抑制由ＰＡＦ诱导的血小板聚集活性。更多还原

【Abstract】 Objective Investigating the chemical constituents of the dried bulbs ofFritillaria Cirrhosa D.Don. Methods Three components were isolated by a series of extractions and chromatographic seperations, and their structures were identified on the basisof spectral data and chemical evidence. Results The structures of three constituents weredetermined as (22R, 25S) - solanidane - 3 β- ol(Ⅰ), thymidine(Ⅱ) and adenosine(Ⅲ).Conclusion Compound Ⅰ was found from genus Fritillaria for the first time. The compoundadenosine was confirmed to be as active inhibitor for platelet aggregation assay which wasinduced by PAF assay.更多还原