【摘要】 目的：检测乳腺癌组织中多药耐药基因的表达并探讨其与ER，PR以及预后的关系。方法：采用S－P免疫织化方法，对120倒乳腺癌组织进行P糖蛋白（PgP），ER／PR表达的检测。结果：乳腺癌组织中P糖蛋白阳性表达为33.3％，ER阳性表达51．7％，PR阳性表达37.5％。P糖蛋白与乳腺癌组织类型及ER／PR天关，PgP，ER／PR阳性表达均与乳腺病预后有关（P＜0.01）。结论：PgP，EE／PR三个指标估计乳腺癌预后比单一指标为好。更多还原

【Abstract】 Objective: To detect expression of MDR in breast carcinoma and to probe relation with ER/PR and prognosis. Methods: Expressions of PgP and ER/pR in 120 cases of breast carcinomas were detected byS- P Immunohistochemistry. Results: The positive rates of PgP, ER and PR were 33. 3 %, 51. 7 % and 37.5 % respectively. It was found that there was a correlation betwecn the expression of PgP and ER/PR and theprognosis(P < 0. 01 ), but there was no difference between their expression and Histopathilogical type. Conclusions: The results suggested that three indexes are better than the single of them to evaluate the prognosis of patients with breast cancer.更多还原