【摘要】 目的：通过对1058例大肠癌的临床病理学研究，分析其病理改变、临床诊治与预后的关系。方法：用组织化学染色观察，临床以内镜诊断及外科手术治疗为主。结果：对于早期大肠癌（病理镜下定为粘膜内癌及粘膜下癌）临床上可以采取活检及电切或局部切除手术治疗。经随访，复发率为2．3％，而做扩大或联合手术时病死率高达13．7％。对于局部扩散者及累及肌层者，宜采取联合手术。联合方案包括：手术、放疗和化疗。其最终目标是改善远期效果。结论：对于大肠癌尽早发现作出明确诊断，即时采取正确手术治疗方案，患者生存率将大为提高，预后较好。更多还原

【Abstract】 To analyze the relationship between the pathological changes, the clinical diagnosis and the prognosis by clinical pathological study on 1058 cases of colon carcinoma. Methods: Histochemical stain method was used, endoscopy technique and surgical therapy were employed in clinic. Results: Biospying and electric rasection or local operation may be adopted in the early stage of colon carcinoma. By following up, the recurrence rate of 2. 3% was found, and the death rate of 13. 7% was observed in the enlarged and combined operations. The operation should be adopted for cancer with local spreading or with muscle invading. The combined scheme consists of operation, radiotherapy and chemitherapy, the final goal is to improve the long - term effect. Conclusion:The survival rate of patient with colon carcinoma will be increased greatly greatly if the right diagnosis is made early and the surgical operaiton is performed in time.更多还原