【摘要】 目的：探讨正电子发射断层扫描（ＰＥＴ） 葡萄糖代谢功能显像在癫癎灶定位诊断中的价值及其与脑电图（ＥＥＧ） 对癫癎灶定位的一致性。方法：５２０ 例ＭＲ 检查正常的癫癎病人，经动态脑电图（ＡＥＥＧ） 和ＰＥＴ检查定位，比较两者的一致性。结果：ＰＥＴ 定位的阳性率为９４－６ ％ ，ＡＥＥＧ 为５４ ％ ，除外ＥＥＧ 定位阴性的２３９ 例，二种定位检查结果完全一致４７－７ ％ （１３４／２８１） ，部分一致占２３－１ ％ （６５／２８１） ，完全不一致者占２９－２ ％ （８２／２８１） 。４ 例皮质脑电图（ＥＣｏＧ） 证实局灶性癫癎样放电与ＰＥＴ 检出的葡萄糖代谢减低区完全一致。结论：ＰＥＴ 是诊断癫癎灶灵敏而有效的方法，对癫癎病灶的定位价值优于ＥＥＧ、ＭＲ、ＣＴ和ＳＰＥＣＴ。更多还原

【Abstract】 Objectives:To explore the diagnostic value of positron emittance tomography(PET) glucose metablism functional imagine in epileptic foci localization and its coincidence with electroencephalography (EEG) localization of epileptic foci. Methods:AEEG and PET localization was made in 520 epileptic patients with normal MR findings and the coincidence of the two methods was compared with each other.Results:The positivity rate of PET and ambulatory EEG(AEEG) localization was 94.6% and 54% respectively. The rate of complete coincidence of the two methods was 47.7%(134/128), partial coincidence was 23.1%(65/281). In four patients, the focal epileptiform discharges confirmed by ECoG was completely coincident with the glucose hypometablism regions in PET. Conclusions:PET might be a more sensitive and effective method in the diagnosis of epileptic foci.更多还原