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肿瘤病人舌苔变化与唾液中人上皮生长因子的关系研究

Study on the Relation Between Tongue Coating and Saliva h-EGF Content of Tumor Patients

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【作者】 詹瑧; 郝晋丰; 汪红; 马永华;

【Author】 Zhan Zhen, Hao Jinfeng △, Wang Hong △△ , Ma Yonghua (College of Basic Medical Sciences, Nanjing University of TCM, Nanjing, Jiangsu, 210029; △ Zhongshan Hospital of Nanjing, Nanjing, Jiangsu, 210014; △△ Affiliated Hospital of Nan

【机构】 南京中医药大学基础医学院!江苏南京210029; 江苏省南京市钟山医院!江苏南京210014; 南京中医药大学附属医院!江苏南京210029;

【摘要】 目的 :研究肿瘤病人舌苔变化与唾液中人上皮生长因子h -EGF含量的关系。方法 :采用1 2 5 I放射免疫分析法 (RIA )。结果 :15 2例肿瘤病人唾液中h -EGF含量为 (4.0 70± 1.0 ) μg L ,明显高于正常人 (3.0 71±1.7) μg L(P <0 .0 1) ,其中 10 2例厚苔者 (占 6 7.1% )的h -EGF含量为 (4.2 70± 1.7) μg L ,也明显高于 5 0例薄苔者 (占 32 .9% )的h -EGF含量 (3.6 91± 1.2 ) μg L (P <0 .0 1)。 结论 :唾液中h -EGF含量与肿瘤病人舌苔增厚密切相关。

【Abstract】 OBJECTIVE:To investigate the relation between tongue coating and saliva h-EGF content of tumor patients.METHOD:The method of 125 I radioimmunoassay(RIA) was applied. RESULT: Among 152 tumor cases, there were 102 cases(67.1%) with thick coating and 50 cases(32.9%) with thin coating. The saliva h-EGF content of tumor patients(4.070±1.0 μg/L) was obviously higher than that of normal person(3.071±1.7 μg/L)( P <0.01), and the h-EGF content of patients with thick coating(4.270±1.7 μg/L) was apparently higher than that of patients with thin coating(3.691±1.2 μg/L)( P <0.01). CONCLUSION:For tumor patients, there is a close relation between saliva h-EGF content and tongue coating thickness.

【关键词】 肿瘤病人; 舌苔; 唾液; 人上皮生长因子; 放射免疫分析;
【Key words】 tumor patients; tongue coating; saliva; h-EGF; RIA;
【基金】 江苏省教委自然科学基金!资助项目 (960 60 )
  • 【文献出处】 南京中医药大学学报 ,JOURNAL OF NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE , 编辑部邮箱 ,1999年06期
  • 【分类号】R241.25
  • 【被引频次】47
  • 【下载频次】181
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