【摘要】 目的：研究真菌与慢性胃粘膜病变的关系。方法：采用真菌培养、生化试验及组织病理学检查方法，对１２９例患各种慢性胃病患者进行了胃液、胃病变部活检组织的检查。其中慢性浅表性胃炎２６例，慢性萎缩性胃炎２２例，胃溃疡４８例，胃癌３３例。正常对照８例。结果：胃液、胃活检组织在各类胃部疾患的真菌检出率分别为：慢性浅表性胃炎为６１．５％和６９．２３％；慢性萎缩性胃炎均为６３．６４％；胃溃疡为７７．０８％和６８．７５％；胃癌为７５．７６％和８４．８４％。正常对照为５０％。经卡方检验，各胃部疾患组与正常对照组相比无统计学差异（ ｐ＞ ０． ０５）。慢性胃粘膜病变所分离真菌为：念珠菌属、酵母菌、青霉、曲霉、链格孢和毛霉菌。结论：慢性胃粘膜病变所分离出的优势菌为白念和类星形念珠菌，次优势菌为曲霉菌和青霉菌。研究结果不能显示胃粘膜疾患与真菌之间的关系。更多还原

【Abstract】 To investigate the relationship between fungi and some chronic gastric mucosal diseases. Methane: Specimens from gastric fluid and lesions were mycologically investigated by culture, biochemical test and histopathologic examination. Results: The specimens were taken from 26 patients with chronic superficial gastritis (CSG),22 with chronic atrophic gastritis (CAG),48 with gastric ulcer(GU),33 with gastric cancer(GC) and 8 normal Persons as control.The results showed that the positive rates of fungi isolation of gastric fluids and biopsy specimens were 61 .5% and 69.23% in CSG,63.64% and 63.64% in CAG,77 .08% and 68.75% in GU,75.76% and 84. 84% in GC, respectively and 50% in the control group. There was no statistical difference between the above mentioned positive rates in the study group and control group. The fungi isolated from the patients were Candida spp, yeasts, Penicillium spp., Aspergilus spp., Alternaria spp. and Mucor. Conclusion: The fungi isolated mainly were C. albicans followed by Aspergillus spp and Penicillium spp. The results of this study do not indicate any correlation between the fungi and the diseases.更多还原