【摘要】 目的　探讨尿微量白蛋白 (ALB)和血、尿α1 微球蛋白 (α1 MG)测定在早期发现糖尿病肾病、高血压肾病中的应用价值。方法　ALB和α1 MG检测采用放射免疫分析法 (RIA) ,血、尿肌酐测定采用碱性苦味酸法。结果血、尿α1 MG、尿ALB阳性率明显高于血Cr阳性率 ,差异有显著性 (P <0 0 0 5 )。尿ALB 尿α1 MG ,血α1 MG 尿α1 MG之比值在两病患者间亦有显著差异 ,高血压肾病高于糖尿病肾病 (P <0 .0 0 1和P <0 0 5 )。结论　α1 MG、ALB的检测对于糖尿病肾病、高血压肾病的早期诊断以及肾功能损伤程度、部位的判定具有一定的价值。更多还原

【Abstract】 Objective To investigate the clinical value of detection on the ALB and α 1 MG in serum and urine in early discovery of the renal diabetes and renal hypertension. And to compare the early differences of ALB with α 1 MG between the two different patients. Methods To test ALB and α 1 MG by RIA and the Cr by alkaline picric acid method.Results the positive rate of serum, urinary α 1 MG and urinary ALB are apparently highter than that of serum Cr. The differences are remarkable(P<0.005).The ratio between ALB and urinary α 1 MG and the ratio between serum α 1 MG and urinary α 1 MG are remarkably different among the patients with these two diseases. namely, the ratios of patients with renal hypertension are higher than those of the renal diabetes (P<0.01 and P<0.05). Conclusions The tests of α 1 MG and ALB are of vital importance in clinic at the early diagnosis of patients with renal diabetes and renal hypertention as well as the injury of renal function.更多还原