【摘要】 目的ADA(1997)推荐仅用FPG作为诊断手段是否可取。将中国人用ADA及WHO(1985)糖尿病诊断标准试以比较。方法对1254名体检者予口服75克葡萄糖的耐量试验。结果ADA(FPG及/或2hPG)的糖尿病诊断检出率分别比WHO及推荐的ADA(FPG)标准提高3%和15%。当2hPG≥11.1mmol/L时,FPG正常者占总数的7%。以ADA(1pg及/或2hPG)为标准,可增加约25%的糖尿病或糖耐量减退的检出率。结论ADA标准仅以FPG作为诊断切割点,仍需进一步完善。ADA(FPG及/或2hPG)可显著提高糖尿病的检出率。更多还原

【Abstract】 To evaluate the American Diabetes Association (ADA) recommended diabetes melli-tus (DM) diognostic criterion (1997) in which merely Fasting plasma glucose (FPG) was applied as the diagnostic approach, a comparison between the diagnoses of (DM) in Chinese with the criteria of ADA and the World Health Organization (WHO) (1985) was performed. Methods A 75 g Oral glucose tolerance test (OGTT) was conducted to 1254 subjects undergoing physical examination. Results The frequency of detection (FOD) of DM with ADA criterion [FPG and/or 2h plasma glucose (2hPG)] was enhanced by 3% and 15% respectively in compare with that of WHO and ADA recommended criteria. 7 % of the subjects presented normal FPG when 2hPG was greater or equal to 11.1 mmol/L. FOD of DM or Impaired glucose tolerance (IGT) could be increased by 25% after using the ADA criterion (FPG and/or 2hPG) . Conclusions Further improvement of ADA criterion is needed in view of the FPG was the only parameter used in diagnosis. FOD of DM can be significantly enhanced by ADA criterion (FPG and/or 2hPG).更多还原