【摘要】 目的：探讨孤立性浆细胞瘤和多发性骨髓瘤间的关系。方法：对27例孤立性浆细胞瘤进行临床分析。结果：提示孤立性浆细胞瘤中的74．07％的患者衍变为多发性骨髓瘤，其衍变的时间长短不一；其衍变和瘤细胞的病理类型明显相关，术后常规的化疗及放疗和其衍变无统计学相关意义。结论：孤立性浆细胞瘤多数将衍变为多发性骨髓瘤，在诊断孤立性浆细胞瘤成立后应将其视为一种单独的疾病，采取恰当的治疗手段能阻止或延后其衍变。更多还原

【Abstract】 Objective: To study the relationship between multiple myeloma and solitary plasmacytoma. Mashed: 27cases of solitary plasmacytoma admitted to our hospital in nearly 17 years were analyzed. Results: 77. 7% of solitaryplasmacytornas developed into multiple myeloma. This development was closely related to the pathological type of solitaryplasma cytomas. Post-operation chemo therapy and rediotherapy had seemed to have nothing to do with the eveloping ofsolitary plasmacytoma. Conclusion: Most of solids plasmacytomas will probably develop into multiple myeloma andtherefore should be considered as a single group of disease.更多还原