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戊二醛交联壳聚糖树脂的制备及其血液相容性研究
STUDIES ON THE PREPARATION OF CROSSLINKED CHITOSAN RESIN AND ITS BLOOD COMPATIBILITY
【摘要】 以戊二醛为交联剂制备了交联壳聚糖树脂,讨论了合成过程中的诸多影响因素,得到了制备的最佳条件.对交联树脂的血液相容性进行了研究.结果表明,树脂对人血清白蛋白的吸附量较低;经过处理后,其血液相容性得到一定程度的改善.
【Abstract】 The crosslinked chitosan resin was prepared by the reaction of glutaraldehyde withchitosan. The effect factors of preparation were studied in detail and the reaction conditions wereoptimized. This type of resin adsorbed little human serum albumin. The blood compatibility ofthe resin can be improved after treatment of elution and reaction with ethanolamine.
【关键词】 壳聚糖[(1,4)-2氨基-2-脱氧-β-葡萄糖];
戊二醛;
血液相容性;
【Key words】 Chitosan [(1; 4 )-2 -amino -2 deoxy- β -D-glucanresins]; Glutaraldehyde; Bloodcompatibility;
【Key words】 Chitosan [(1; 4 )-2 -amino -2 deoxy- β -D-glucanresins]; Glutaraldehyde; Bloodcompatibility;
【基金】 国家自然科学基金!59503005
- 【文献出处】 离子交换与吸附 ,ION EXCHANGE AND ADSORPTION , 编辑部邮箱 ,1999年05期
- 【分类号】O636
- 【被引频次】36
- 【下载频次】737