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儿童屈光参差性和斜视性弱视多导图形视觉诱发电位的研究

Investigation of multi-channel pattern reversal visual evoked potentials of anisometropic amblyopia and introtropic amblyopia

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【作者】 陈林义胡兵印路周逸峰开远忠

【Author】 Chen Linyi,Hu Bing,Yin Lu,et al.Center for Children’s amblyopia and Strabismus,USTC,Hefei 230026

【机构】 中国科学技术大学儿童弱视、斜视研究治疗中心

【摘要】 目的通过用多导图形视觉诱发电位(P-VEP)进一步研究儿童弱视的发病机制及两种弱视之间的相互关系。方法采用16导视觉诱发电位仪,分别检查了25例屈光参差性弱视和33例内斜视性弱视,将检查的P-VEP三个主要参数分别与正常对照组和弱视眼对侧眼的相应参数进行了比较。结果两种类型弱视的三个主要参数的平均结果都发生了明显的改变,内斜视性弱视的对侧眼与正常对照组相比N1、P1波的潜伏期也明显延长,振幅下降,说明内斜视对侧眼并非正常;结果还提示屈光参差性弱视其振幅比值较其对侧眼小于0.8、潜伏期大于5ms,可作为诊断的参考依据。结论临床上根据P-VEP的检查结果来判断弱视是可靠的

【Abstract】 Objectives To further investigate the mechanism of amplyopia and the relationship between two kinds of amblyopias. Method P-VEP recording 14-channel signal analysis 25 cases of anisometropic amblyopia and 33 cases of introtropic amblyopia were checkedb using The three important parameters of either the normal control or the fellow eyes of amblyopia patient were compared each other.Results The average of these three important parameters of the two kinds of amblyopias all change significantly.There are significant delays of the latencies of N 1、P 1,when amblyopia eye is compared with either normal control or the fellow eye of introtropic amblyopia patient.And the distribution of the amplitudes is similar.This shows that the fellow eyes of introtropic amblyopia patients are not normal eyes,Our results also provide an index for amblyopia diagnosis if the amplitude of anisometropic amblyopia is lower less than 0.8 and the latency is longer more than 5ms by comparing with the fellow eye.Conclusion It’s feasable for amblyopia diagnosis based on the P-VEP method.

  • 【文献出处】 临床眼科杂志 ,JOURNAL OF CLINICAL OPHTHALMOLOGY , 编辑部邮箱 ,1999年02期
  • 【分类号】R777.44
  • 【被引频次】3
  • 【下载频次】68
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