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口腔扁平苔藓损害组织中幽门螺旋杆菌DNA的原位检测及其意义
The detection and effect of helicobacter pylori in the lesions of oral lichen planus.
【摘要】 为了进一步探讨口腔扁平苔藓(OLP)与幽门螺旋杆菌(HP)的关系,本研究应用非放射性DIG系统的原位杂交技术对20例HP-PCR阳性的OLP患者作HP-DNA的检测。结果显示:在20例OLP的损害组织中,18例为HP-DNA阳性,2例为阴性,而对照组均为阴性。结果提示OLP损害组织中HP所致的病理变化可能是某些OLP的发病基础。
【Abstract】 In order to discuss the relationship of oral lichen planus(OLP) and helicobacter pylori(HP),in situ hybridization was applied to detect HP DNA in the lesions of 20 OLP cases who were HP PCR positive. The result showed that 18 of 20 OLP cases had positiveness of HP DNA and 2 negativeness. It is indicated that HP in the lesions of OLP may result in pathological change which may be the pathogenic basis of OLP.
【关键词】 口腔扁平苔藓;
幽门螺旋杆菌;
原位杂交;
【Key words】 Oral Lichen Planus Helicobacter Pylori In Situ Hybridization;
【Key words】 Oral Lichen Planus Helicobacter Pylori In Situ Hybridization;
【基金】 深圳建安医药公司资助
- 【文献出处】 临床口腔医学杂志 ,JOURNAL OF CLINICAL STOMATOLOGY , 编辑部邮箱 ,1999年02期
- 【被引频次】12
- 【下载频次】77