【摘要】 探讨如何减少手术对垂体瘤患者造成的创伤，从而达到微创伤或低创伤治疗。方法：对１２例患者在鼻内窥镜下进行经鼻腔－蝶窦垂体瘤切除术。全麻，内窥镜下经一侧鼻腔、蝶窦入路，打开鞍底骨质及硬脑膜，直视下切除肿瘤。结果：除１例二次手术的生长激素腺瘤患者死于术后颅内出血外，其余恢复顺利。随访７个月～１．５年，有９例内分泌指标恢复正常，其中８例术前存在视力障碍者，术后均有不同程度的恢复。结论：内窥镜具有照明好，视野清楚之优点，临床应用不仅能提高手术的准确性和安全性，还能减少对正常组织的损伤。更多还原

【Abstract】 . Objective:For reducing surgical trauma to patients of pituitary tumor. Method: 12 patients of pituitary tumor were treated with endoscopy by nasal cavity and sphenoid sinus under general anaesthesia. Result: Except one died of bleeding within cranial cavity after operation,the rest recovered smoothly without severe complications. During 7 months to one and half year follwing-up,the function of endocrine in 9 cases resumed to normaland 8 of their vision improved to some extent. Conclusion:The good illumination and clear visual field under endoscopy could improve the accuracy and security of operation and minimize the injury to normal tissue. But forlarge or recurrent tumors,this approach should be selected carfully.更多还原