【摘要】 目的：探讨一氧化氮（NO）在戊四唑（PTZ）点燃发病机理中的作用．方法：每天注射PTZ建立大鼠点燃模型，运用组织化学方法观察海马、杏仁核一氧化氮合酶（NOS）阳性神经元变化．结果：点燃后海马、杏仁核内NOS阳性神经元明显增多．结论：NO促进了戊四唑点燃的形成．更多还原

【Abstract】 Aim:To explore the pathogenetic role of nitric oxide in pentylenetetraZol (PTZ)- kindling. Methods: The rat kindling model was induced by daily injection of PTZ. Wc observed the alteraion in NOS positive neurons in the rat hippocampus and amygdala of by biochemical methods.Results: The NOS positive neurons in the rat hippocampus and amygdala after kindling were increased significantly. Conclution:NO might promote the formation of kindling by PTZ.更多还原