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MLTC上清对同种肿瘤细胞的杀伤作用
The Kill Effects of MLTC Supernatant Fluid on Tumor Cell in Homogeneity
【摘要】 为探讨淋巴细胞与肿瘤细胞混合培养中淋巴细胞分泌的细胞毒因子,采用3 H Td R 掺入试验,测定淋巴细胞和肿瘤细胞混合培养( M L T C)的上清液对艾氏腹水癌细胞( E A C)的细胞毒作用以及胸腺素对它的影响⒚结果表明:混合培养时间不同的 M L T C 上清对不同瘤龄的 E A C 均具有明显的杀伤作用( P< 0.01);胸腺素能显著增强 M L T C 上清对 E A C 的细胞毒效应( P< 0.01)⒚说明在 M L T C 中,肿瘤细胞能刺激淋巴细胞转化,分泌特异的细胞因子来杀伤同种肿瘤细胞⒚
【Abstract】 H TdR incubated experiment has been conducted to test the cytotoxicity of MLTC supernatant fluids on Ehrlich Ascitic Carinomai (EAC) and thymosin as well. The result showed that MLTC supernatant fluids with different mixed culture time all had obvious killing effects on the different aged EAC ( P <0.01); thymosin could significantly strengthen the cytotoxicity of the MLTC supernatant fluids on EAC cells ( P < 0.01).
【关键词】 淋巴-肿瘤细胞混合培养;
胸腺素;
细胞毒作用;
艾氏腹水癌;
【Key words】 mixed lymphocyte tumor culture (MLTC); thymosin; cytotoxicity; Ehrlich Ascitic Carinomai (EAC);
【Key words】 mixed lymphocyte tumor culture (MLTC); thymosin; cytotoxicity; Ehrlich Ascitic Carinomai (EAC);
- 【文献出处】 科技通报 ,BULLETIN OF SCIENCE AND TECHNOLOGY , 编辑部邮箱 ,1999年05期
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