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被孢霉生物合成花生四烯酸的初步研究

PRELIMINARY STUDIES ON ARACHIDONIC ACID PRODUCTION OF MORTIERELLA

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【作者】 鲍时翔黄惠琴朱法科林炜铁姚汝华

【Author】 Bao Shi-Xiang; Huang Hui-Qing;(National Key Biotechnology Laboratory for Tropical crops, China Academy of Tropical Crops, Haikou 571101)Zhu Fa-Ke; Lin Wei-Tie; Yao Ru-Hua(Department of Bioengineering, South China University of Technology , Guangzhou 51064

【机构】 中国热带农业科学院热带作物生物技术国家重点实验室!海口571101华南理工大学生物工程系!广州510641

【摘要】 花生四烯酸不仅是细胞膜的重要成分,在维持细胞膜的结构与功能上发挥重要作用,而且是人体前列腺素合成的前体物质,对人体生理功能具有重要的调节作用。近年来研究发现,花生四烯酸在保护皮肤、降低胆固醇、抑制血小板聚集、提高免疫能力、促进胎儿发育等方面具有独特的...

【Abstract】 Mortierella sp. M10 was used to produce arachidonic acid. The effects of carbon source, glucose concentration, vegetable oil, etc. on the cell growth and arachidonic acid production were investigated. Glucose was the most effective carbon source for the production of arachidonic acid. Addition of corn oil, olive oil and soybean oil to the medium at the low concentration increased the accumulation of arachidonic acid.After fermentation in a 5L fermenter in the hasal medium containing 100g/L glucose and 2% olive oil, the production of arachidonic acid reached 0.95g/L.

【关键词】 被孢霉花生四烯酸发酵油脂
【Key words】 MortierellaArachidonic acidFermentationLipid
【基金】 中国博士后科学基金;中博基!(1996)2号
  • 【分类号】Q939.5
  • 【被引频次】26
  • 【下载频次】177
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