【摘要】 目的：研究褪黑激素对大鼠肾组织结构的影响．材料和方法：连续３０天给初老大鼠补充褪黑激素，用光、电镜观察及计算机图像分析。结果：实验组大鼠肾组织结构清晰，肾小体变小，集合管变粗；近曲小管和集合管上皮细胞超微结构老化现象改善。结论：褪黑激素对抗肾组织结构的退行性变及老化、延缓肾功能衰退有一定的作用。更多还原

【Abstract】 In the paper, we investigated the effect of melatonin on aging kidney of newly-old rats with light microscopic, electronic microscopic and computer image analysis. The results were as follows: The renal tissue of the experimental group was normal and clear. The renal corpuscle and the collecting tubule of the experimental group were smaller and larger than that of the control group. The aging of the ultrastructure of the proximal tubule epithelium and collecting tubule epithelium of the experimental rats got improved. It suggests that melatonin may have an effect on kidney aging and kidney function.更多还原