【摘要】 目的探索微波辐射对中枢神经系统影响的机理。方法以２４５０ＭＨｚ微波理疗机为辐射源，在照射总剂量相同的条件下对ＬＡＣＡ纯种小白鼠分别进行２ｄ、７ｄ和１４ｄ照射，照射强度均为５ｍＷ／ｃｍ２。结果照射组小鼠大脑皮层的单胺氧化酶活性均较对照组高（Ｐ＜０．０５）；２ｄ、７ｄ组小鼠脑内去甲肾上腺素含量较对照组明显减少（Ｐ＜０．００１）；各照射组５羟吲哚乙酸含量均高于对照组，其中２ｄ和１４ｄ组显著升高（Ｐ＜０．００１）。结论微波辐射会使脑内单胺类神经递质代谢发生异常更多还原

【Abstract】 Objective To investigate the mechanism of effects of microwave irradiation on central nervous system (CNS). Method 72 male LACA mice were irradiated with 2450 MHz microwave for 2,7 or 14 days respectively with the same total incident power density of 5 mW/cm2. Result After exposure, every group showed an increase of monoaminoxidase(MAO) in the cerebral cortex as compared with the control ( P <0.001 ). The norepinephrine(NE) content were significantly reduced after twoday or twoweek exposure( P <0.05). The 5hydroxyindoleacetic acid (5HIAA) content, the main metabolite of 5hydroxytryptamine (5HT), were significantly increased after twoday or 7 day exposure ( P <0.001). ConclusionZ The metabolic abnormity of neurotransmitters in the central nervous system may be one of the factors causing disorders in the microwave operators.更多还原