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+Gz作用下心电图QT间期的改变及其意义

Changes in QT Interval of Electrocardiogram under +Gz Acceleration and Its Significance.

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【作者】 吴斌谢宝生薛月英路盛强由广兴刘兴华

【Author】 WU Bin,XIE Bao sheng,XUE Yue ying,LU Sheng qiang,YOU Guang xing,LIU Xing hua.Space Medicine & Medical Engineering,1999,12(5):328~332

【机构】 航天医学工程研究所!北京100094

【摘要】 目的探讨能否用 Q T 间期来预测飞行员对+ Gz 应激的反应情况。方法37 名空军飞行员在人用离心机上经受峰值为4 G 的正向加速度作用,根据被试者对+ Gz 应激反应的不同,将其分成 A组( 反应良好组,n = 18) 、 B 组( 反应亢进组,n = 14) 和 C 组( 反应抑制组,n = 1) 。实验结束后测量+ Gz 作用前、中、后心电图的 Q T 间期和 R R 间期,并对能够测量出 Q T 间期的33 人(89 .2 % ) 的数据进行统计分析。结果 + Gz 作用中 Q T 间期和 R R 间期明显缩短, Q T 间期对 R R 间期的敏感性明显增加( 与+ Gz 作用前比, P< 0 .001) ; A 组与 B 组相比,+ Gz 作用中 Q T 间期对 R R 间期的敏感性差异显著( P< 0 .001) ;用+ Gz 作用中的 Q T 间期和 R R 间期建立的判别方程有效,其总的判别正确率为81 .8 % 。结论+ Gz 作用下 Q T 间期的改变与自主神经均衡性的变化有关;用心电图的 Q T 间期和 R R 间期通过判别方程可以预测飞行员对+ Gz 应激的反应情况,本研究提出的指标和方法有可能在 G- L O C 预警系统中得到应用。

【Abstract】 Objective To define whether QT interval could be used to predict the response of pilots to +Gz stress. Method 37 pilots underwent +4 Gz acceleration on a human centrifuge.According to their responses to +Gz stress, subjects were divided into group A (good reaction group, n=18), group B (hyperfunction reaction group,n=14) and group C (inhibition reaction group,n=1). QT and RR interval were measured pre-,during and post G. The data of 33 subjects(89.2%) whose QT interval could be measured were analyzed statistically. Result During +Gz, QT and RR interval were shortened and sensitivity of QT interval to RR interval was augmented significantly (vs. pre G, P< 0.001 );group B had higher sensitivity of QT interval to RR interval during +Gz (P<0.001, as compared with group A);discrimination functions established by QT and RR interval during +Gz were efficient and their accurate judgement rate was 81.8%. Conclusion The Changes in QT interval of ECG were related to autonomic nervous imbalance under +Gz; QT interval and RR interval could be used to predict the response of pilots to +Gz stress. These suggested that the parameters and method in this study might be used in G LOC warning system.

  • 【文献出处】 航天医学与医学工程 ,SPACE MEDICINE & MEDICAL ENGINEERING , 编辑部邮箱 ,1999年05期
  • 【分类号】R852.21
  • 【被引频次】4
  • 【下载频次】52
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