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胎儿视皮质神经元发育的立体学定量分析

Stereological quantitative analysis on development of the visual cortex neurons in human fetus

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【作者】 纳冬梅王荣华孙强安中平张宝东宋铁军

【Author】 NA Dong mei,WANG Rong hua,SUN Qiang,et al (Department of Neurology,Inner Mengolia Baotou Iron and Steel Worker’s Hospital,Baotou 014000,China)

【机构】 包头市包钢职工医院神经内科!内蒙古包头014000哈尔滨医科大学组胚教研室!黑龙江哈尔滨150086哈尔滨医科大学组胚教研室!黑龙江哈尔

【摘要】 本实验取材自14 例流产的正常胎儿,胎龄12 ~40 周,对其视皮质神经元进行立体定量分析。结果表明,视皮质神经元发育过程中核质比例逐渐减小;细胞核体密度逐渐减小,核仁与胞质的体密度呈上升趋势;细胞质内线粒体、粗面内质网、核糖体的体密度呈明显上升趋势,而滑面内质网、高尔基复合体及溶酶体的体密度均有不同程度的上升。

【Abstract】 With the electron microscope,we observed neurons in visual cortex (from 14 normal fetus whose gestational ages were 12~14 weeks) and then analysed them by stereology method.The results showed that in development of neurons in visual cortex,nucleoplasmic ratio decreased with gestational age;the volume density of nucleus decreased with development,and the volume density of nucleolus and cytoplasm increased;the volume density of mitochondria,rough endoplasmic reticulum and ribosome tended upwards obviously,and the volume density of smooth endoplasmic reticulum,Golgi complex and lysosome tended upwards to various degrees,too.

【关键词】 视皮质神经元发育体视学胎儿
【Key words】 visual cortex neuronsdevelopmentstereology
  • 【文献出处】 哈尔滨医科大学学报 ,JOURNAL OF HARBIN MEDICAL UNIVERSITY , 编辑部邮箱 ,1999年06期
  • 【分类号】R321
  • 【下载频次】18
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