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穿琥宁及其复方注射液解热作用的比较研究

STUDY ON ANTIPYRETIC EFFECT OF CHUANHUNING COMPOUND INJECTION IN COMPARISON WITH OTHER RELATIVE PREPARATIONS

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【作者】 王炳南贺英菊王祥龙波郭玲晓张运伟丁志勇陈林杜万军

【Author】 Wang Bingnan He Yingju Wang Xiang Long Bo (School Pharmacy, West China University of Medical Sciences Chengdu 610041) Guo Lingxiao Zhang Yunwei Ding Zhiyong Chen Lin Du Wanjun (Wuliangye Group Yibin Pharmaceutical Factory Yibin 644002)

【机构】 华西医科大学药学院!成都610041五粮液集团-宜宾制药厂!宜宾644002五?

【摘要】 通过热反应法测量家兔给药前后直肠温度变化的数据,证明了以穿琥宁为主药,配伍适量异丙嗪,具有药物协同作用的复方穿琥宁制剂的解热作用优于单方制剂。

【Abstract】 The antipyretic effects of Chuanhuning compound injections with low and normal doses were studied in this paper compared with Chuanhuning simplex injections with low and normal doses, promethazine simplex and normal saline injections. The results showed that the antipyretic effect of Chuanhuning compound injection with normal dose was stronger than that of any other relative preparations and the antipyretic effect of Chuanhuning compound injection with low dose was stronger than that of Chuanhuning simplex injection with low dose, promethazine simplex injection, normal saline injection and equivalent to that of Chuanhuning simplex injection with normal dose, both statistically and pharmacodynamically, respectively. The reasonable explanation should be atributed to the synergism of drugs.

  • 【文献出处】 华西药学杂志 ,WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES , 编辑部邮箱 ,1999年04期
  • 【分类号】R285
  • 【被引频次】5
  • 【下载频次】53
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