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非经典铂类抗癌配合物的进展近况
THE DEVELOPMENT SITUATION OF NONCLASSICAL PLATINUM ANTITUMOR COMPLEXES
【摘要】 介绍了非经典铂类抗癌配合物的发展概况,并按中心离子价态、配体及配合物结构特征对其进行分类,讨论其构效关系,对新的铂类抗癌药物的研制具有一定的指导意义
【Abstract】 The development of nonclassical platinum antitumor complexes is introduced These complexes are classified according to the characteristics of centralion oxidation state,ligands and the structure.The structureactivity relationships are discussed indicating that there is certain instructive significance to the exploration of the novel platinum antitumor drugs.
【关键词】 抗癌药物;
铂类配合物;
构效关系;
进展;
【Key words】 antitumor drugs; platinum complex; structureactivity relationship; development;
【Key words】 antitumor drugs; platinum complex; structureactivity relationship; development;
【基金】 浙江省自然科学基金,浙江海正药业有限公司资助项目
- 【文献出处】 化学研究与应用 ,CHEMICAL RESEARCH AND APPLICATION , 编辑部邮箱 ,1999年03期
- 【分类号】O614.826
- 【被引频次】17
- 【下载频次】360