节点文献
应用聚合酶链反应技术检测腮腺腺淋巴瘤中EB病毒整合
Detection of Epstein Barr Viral Genome in Tumor Cells of Warthin’s Tumor of Parotid Gland
【摘要】 目的:研究腮腺腺淋巴瘤(Warthin's瘤)和EB病毒感染之间的关系。方法:应用聚合酶链反应技术检测75例Warthin's瘤,20例正常腮腺组织的EB病毒DNA整合情况。结果:62例单发Warthin's瘤中19例检出EB病毒DNA整合,13例双侧或单侧多发Warthin's瘤中9例检测出EB病毒DNA整合。20例正常腮腺组织中3例EB病毒DNA整合阳性。结论:EB病毒感染与双侧或单侧多发Warthin's瘤有关。
【Abstract】 Objective: To evaluate the relations between Warthin’s tumors of salivary gland and Epstein Barr virus (EBV). Methods: 75 cases of salivary gland Warthin’s tumor and 20 cases of normal salivary gland tissue were examined for to detect EBV genoma by using the polymerase chain reaction (PCR) of DNA, 62 cases of single Warthin’s tumor and 13 cases of multiple/bilateral Warthin’s tumor’s .Results: EBV DNA was detected in 13 cases of single Wathin’s tumors, 9 cases of multiple/bilateral Warthin’s tumor and 3 cases of normal salivary gland. Conclusion: There was a close relationship between EBV and multiple/bilateral Warthin’s tumors.
【Key words】 Epstein Barr virus\ \ Warthin’s tumor\ \ polymerase chain reaction;
- 【文献出处】 华西口腔医学杂志 ,WEST CHINA JOURNAL FOF STOMATOLOGY , 编辑部邮箱 ,1999年02期
- 【分类号】R446.5
- 【被引频次】7
- 【下载频次】43