【摘要】 在电镜下观察了加味温胆汤对Ｄ－半乳糖亚急性衰老大鼠大脑皮质神经元超微结构改变的影响，并对其主要细胞器进行了计量分析。结果表明：模型组脂褐素数量较正常组增多（Ｐ＜０．０５），线粒体则减少（Ｐ＜０．０５）同时还发现溶酶体、脂褐素大小形态不规则，线粒体肿胀、变性、嵴断裂、空泡样变，核膜内褶断裂，核仁边移等衰老改变，而加味温胆汤则使上述变性程度减轻，从而表明该方能延缓脑衰老，并提示该方可能具有稳定神经细胞生物膜系统作用。更多还原

【Abstract】 The influence of supplemented gallbladder-warming decoction on cerebral cortex ultrastuctuer of subacute senile rats was observed and analised.The results showed that in model group,lipofuscin was increased(P<0 05),mitochondriona was decreased(P<0 05),the size of lipofuscin was irregular,mitochondrion was turgescent,nuclear membrane was broken and nucleolus was marginated.Supplemented gallbladder-warming decoction could slow the above changes.It suggested that supplemented gallbladder-warming decoction could delay the senility of brain and stabilize the system of nerve ecell biomembrane.更多还原