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耐甲氧西林葡萄球菌的临床流行病学研究

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【摘要】 目的研究葡萄球菌的感染及耐药状况,有效控制耐甲氧西林的葡萄球菌,为临床合理选用抗生素提供可靠依据。方法常规法分离菌株,药敏试验用K-β法、MIC法。MRS测定用琼脂筛选法。分析门诊及住院病人MRS产生情况。结果285株葡萄球菌测得MRS检出率51.6%,MRSA及MRCNS检出率分别是59.6%和48.6%,测得其对稳可信和亚胺硫霉素的敏感率分别为100%的80%以上,而对其它抗生素是现多重或交叉耐药现象,结论MRS感染问题日趋严重,应加强其耐药性监测,临床治疗MRS感染,稳可信应做为首选。

【Abstract】 To Study the infection and resistant condition of staphylococcus, control theMRS effectively and offer reliable clinical evidence to choose antibiotics rarnably. Methods Usingcommon method to separate the bacteria stains and using K- F method, MIC method to do the antimicrobil susceptibility testing. Using apar selective way to MRS. Analyzing the MRS condition of outpatients and inpatients. Results The detection rates of MRS, MRSA and MRCNS from 285 strains ofstaphylococcus are 51. 6 %, 59. 6% and 48. 6% respectively, the sensitive rate against vancocin and limipenem are 100% and more than 80%, and multiple or cross resistant appearance to other antibioticsexists. Chnclusions The problem of MRS infection is more and more serious. It should be done to detect it’s resistance and vancocin should be the first choice to cure MRS infection in clinic.

  • 【文献出处】 河南职工医学院学报 ,Journal of Henan Medical College For Staff and Workers , 编辑部邮箱 ,1999年04期
  • 【分类号】R181.3
  • 【下载频次】21
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