【摘要】 探讨生脉散对胎儿宫内发育迟缓患者（ＩＵＧＲ）的疗效及对外周血一氧化氮（ＮＯ）和内皮素－１ （ＥＴ－１）水平的影响；方法：对１８例ＩＵＧＲ患者用生脉散治疗；结果：ＩＵＧＲ治疗前ＮＯ水平明显低于治疗后水平 和正常组（Ｐ＜０．０５）；结论：生脉散能有效地清除氧自由基，使ＮＯ的灭活减少，ＮＯ水平升高，恢复ＮＯ／ＥＴ－１之 间的平衡，从而降低子宫血流阻力，改善胎盘血流灌注，促进ＩＵＧＲ儿的生长发育。更多还原

【Abstract】 Objective: To explore effect of shengmaisan on NO and ET-1 in peripheral blood of intrauterine growth dationsn(IUGR) patients. Motheds: 18 patients with IUGR were treated with Shengmaisan which is composed of traditional herbs. Results: NO concentrations of the patients before treatment is sigificantly lower than that after treatment, and the NO concentration of control group(P<0.05). Conclusion: The results showed that Shengmaisan could effectively eliminate free oxygen group, reduced inactivatiovation of NO, increase the content of NO and restore the balance NO and ET-1. So, it was thought that Shengmaisan can reduce the resistance of blood circulation in uterus, improve the blood circulation of placenta and promote the growth and development of IUGR.更多还原