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肱动脉二维超声检测硝酸甘油耐受性

Detection of nitroglycerin tolerance by brachial artery two dimensional ultrasonography

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【作者】 刘兴鹏魏经汉张隽董建增秦石城魏太星

【Author】 Liu Xingpeng Wei Jinghan Zhang Jun et al (Department of Cardiology,The First Affiliated Hospital of Henan Medical University,Zhengzhou 450052)

【机构】 河南医科大学第一附属医院心内科!郑州450052河南医科大学第一附属医院呼吸内科河南医科大学第一附属医院超声科

【摘要】 目的: 评价应用肱动脉二维超声检测硝酸甘油( NTG) 耐受性的临床价值。方法:35 例充血性心力衰竭患者持续应用NTG 贴片6 日,于用药前后,应用二维超声测定舌下含化NTG 04 mg 对肱动脉内径的影响。结果: 应用NTG 贴片前舌下含化NTG04 mg ,肱动脉内径的舒扩张百分率为1224 % ±555 % ,持续应用NTG 贴片6日后,该反应降至568 % ±204 % ( P< 0 .01) 。结论: 临床应用肱动脉二维超声检测NTG 耐受性方法简便、可靠实用

【Abstract】 Objective: To evaluate the clinical value of using brachial artery two dimensional ultrasonography to detect the nitroglycerin tolerance.Methods: Two dimensional ultrasonography was used to measure the diameter of brachial artery at baseline and after 6 days of constant nitroglycerin therapy in 35 patients with congestive heart failure.At each study,brachial artery dilator response to 0.4 mg sublingual nitroglycerin was measured.Results: The results showed the brachial artery dilated 12.24%±5.55% to sublingual nitroglycerin at baseline.After 6 days of constant nitroglycerin therapy,the response was only 5.68%±2.04%( P <0.01).Conclusion: The results suggested that this method is a simple,reliable and useful tool for the clinical detection of nitroglycerin tolerance.

  • 【文献出处】 河南医学研究 ,HENAN MEDICAL RESEARCH , 编辑部邮箱 ,1999年03期
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