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缺氧缺血性脑病脑水肿量化诊断方法探讨

Quantitative diagnosis of hypoxic ischemic encephlopathy

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【作者】 管婉华陈欣林周晓珊李宁

【Author】 Guan Wanhua, Chen Xinlin, Zhuo Xiaoshan,Li Ning Hubei Maternal and Children Health Hospital, Wuhan 430070

【机构】 湖北省妇幼保健院

【摘要】 目的:为了探讨缺氧缺血性脑病(HIE)量化诊断方法。方法:对正常新生儿35例,HIE15例,使用Acuson128×P/10电脑声像仪,V714扇扩探头及L7高频线阵探头,经耳郭上方双侧颞侧,直接检测蛛网膜与脑沟及蛛网膜与脑回的间隙,并同时测双侧大脑皮层血流,于日龄1、3、5d连续检测。结果:正常新生儿蛛网膜下腔间隙显示清晰,结构稳定,蛛网膜与脑沟之间的间隙为193~2.33mm,与脑回之间的间隙144~164mm,而15例HIE患儿大脑皮层沟、回结构显示不清,沟、回起伏结构消失,蛛网膜下腔间隙显示不清。动态观察随患儿病情逐渐好转,蛛网膜与脑沟之间的间隙由076mm增至191mm,与脑回之间的间隙由006mm增至029mm。结论:测量蛛网膜下腔间隙,方法简便、无创、数据可靠,可作为HIE脑水肿量化诊断指标。

【Abstract】 Aim:To study quantitative diagnosis of hypoxic ischemic encephlopathy(HIE). Methods:The depths of the subarachnoid and the bloodstream of each side of cerebral cotex in 35 normal infants and 15 HIE at the ages of 1,3 and 5 days were examined by ultrasonography. Results: In normal infants, the subarachnoid spaces were showed clearly, the structure was stable, the space between the arachhoid and the sulcus was 1.93~2 33 mm, and the space between the arachnoid and the gyrus was 1.44~1.64 mm. The wave structures of the sulcus and gyrus of 15 HIE infants were not clear. With HIE infant’s recovering,the spaces between the arachnoid and the sulcus, and the gyrus extended to 1.91 mm and 0.29 mm, respectively. Conclusion:The method measuring the arachnoid is easy and reliable.It can be used as the index of the quantitative diagonosis when the brain edema is diagnosed.

  • 【文献出处】 河南医科大学学报 ,Journal of Henan Medical University , 编辑部邮箱 ,1999年01期
  • 【分类号】R722.120.4
  • 【下载频次】36
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