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近交培育的豫医无毛小鼠H抗原系统的同源性
Study on the homology of H antigens in inbred Yuyi hairless mice
【摘要】 目的:研究豫医无毛小鼠H 抗原系统的同源性。方法:采用近交培育20 代2 月龄雌性豫医无毛小鼠皮肤异体移植法。结果:经100 d 观察,受试小鼠无急慢性排斥反应发生,移植皮片全部为永久性接受。结论:豫医无毛小鼠突变种群经20 代近交培育,组织相容性抗原一致,基因具有高度同源性
【Abstract】 Aim:To study the homology of H antigens in Yuyi hairless (YYHL)mice.Methods:Skin isografting was performed on inbred YYHL mice at age of 2 months.Result:There were no acute or chronic exclusions with the tested mice after being observed for 100 days.All the grafts were taken in permanently.Conclusion:The results suggest that the histocompatibility antigens are identical and the genes are provided with highly isogenicity in the mutant strain of YYHL mice after inbeding for 20 generations.
【关键词】 皮肤;
异体移植;
近交;
豫医无毛小鼠;
H抗原;
同源性;
【Key words】 isografting; inbred; Yuyi Hairless Mice; H antigens; isogenicity;
【Key words】 isografting; inbred; Yuyi Hairless Mice; H antigens; isogenicity;
【基金】 河南省科技攻关资助项目
- 【文献出处】 河南医科大学学报 ,JOURNA OF HENAN MEDICAL UNIVERSITY , 编辑部邮箱 ,1999年04期
- 【分类号】R-332
- 【被引频次】3
- 【下载频次】27