【摘要】 目的：对正常压力脑积水（NPH）病人行低压脑室腹腔分流（LPV）和中压脑室腹腔分流（MPV）的结果比较和总结。方法：均用美国生产的脑室腹腔引流管，20例NPH病人平均分为两组，每组10人，即LPv（压力40±10mmH2O）组和MPV（压力100±10mmH2O）组。NPH的主要诊断标准为进行性痴呆、步态失调和尿便失禁。术后1、3、6、9、12个月复查。平均进步：LPV组为70％，MPV组为50％；明显进步乃至症状完全消失者LPV组为50％，MPV组则为25％。整个结果说明LPV组效果较好。LPV组脑室缩小较MPV组明显，但硬膜下积液发生率为70％，而MPV组为30％，然而硬膜下积液对病人影响是不明显的。结论：对NPH病人LPV分流较MPV好，NPH的治疗以LPV分流为宜。更多还原

【Abstract】 Objective: The goal of this prospective study was to compare outcome after placement a low or medium pressure shunt in patients with normal pressure hydrocephalus (NPH). Methods: Twenty patients with NPH were randomized to receive a low pressure ventriculoperitoneal shunt (LPV: 40 ± 10 mmH2O) or medium pressure ventriculoperitoneal shunt (MPV100± 10 mmH2O). NPH clinical syndrome was presented with dementia, gait disturbance and uracratia. Results:Patients were examined prior to and 1, 3, 6, 9 and 12 monts after surgery. Improvement was found in 70% of patients with LPV shunt and in 50% of patients with MPV shunt. A marked to excellent inprovement in 50% of patients with LPV shunt and 25% of patients with MPV shunt. All outcome measures indicated trends in favor of the LPV shunt group. Reduction in ventricular size wae also significantly greater for patients in the LPV shunt group. Subdural effusion occured in 70% of patients with an LPV shunt and 30% of patients with MPV shunt; however, their influence on patient; outcome was limited. Cooclusions: Outare was better for patients who had an LPV shunt than for those with an MPV shunt. The authors advise that patients with NPH be treated with an LPV shunt.更多还原