【摘要】 对５０例重型颅脑损伤患者进行颅内压（ＩＣＰ）与脑灌注压（ＣＰＰ）连续监测，并根据监测结果及时采取相应的治疗护理措施（监护组）；与５０例未行连续监测，按常规临床观察进行治疗护理的患者（对照组）进行预后比较。结果表明：监护组并发症比对照组明显减少，致残率及死亡率明显低于对照组（Ｐ＜００１）。观察ＩＣＰ、ＣＰＰ结果显示：ＩＣＰ＜２００ｋＰａ、ＣＰＰ＞９３３ｋＰａ的患者预后良好；ＩＣＰ＞８００ｋＰａ、ＣＰＰ＜６６７ｋＰａ者预后较差。提示：对重型颅脑损伤患者施行连续ＩＣＰ、ＣＰＰ监护，有利于了解病情变化，及时采取有效的治疗护理措施，对降低致残率及死亡率具有临床应用价值。更多还原

【Abstract】 Continuous monitoring of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) was performed in 50 patients with severe brain injury. According to the monitoring results, corresponding treatment and nursing care were given timely (group Ⅰ).Other 50 patients without undergoing continuous montoring obtained the treatment and nursing in terms of ordinary clinical observation and served as control group (groupⅡ).The prognosis comparison was conducted between the two groups. The results showed that in group I the patients with complications were decreased significantly as compared with group Ⅱ and disability rate and mortality obviously lower than in group Ⅱ( P <0 01).The ICP and CPP measurements demonstrated that the patients with ICP<2 00 kPa and CPP>9 33 kPa had a good prognosis,while the patients with ICP>8 00 kPa and CPP<6 67 kPa had a worse prognosis. It was suggested that continuous ICP and CPP monitoring for the patients with servere brain injury was of great clinical value for knowing the diseased conditions, carrying out effective treatment and reducing the disability rate and mortality.更多还原