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白细胞介素8对寻常型银屑病病理形成的动态研究
Study on continous effect taken by IL-8 to formation of dermat pathology of psoriasis
【摘要】 目的:为研究白细胞介素8( I L- 8) ,在寻常型银屑病病理形成的持续性作用;方法:我们采取按时间顺序连续性取材,对其用抗 I L- 8 抗体进行免疫组化测定;结果:早期病理变化轻微的皮损已经有了 I L- 8 的表达,随着病理变化的日益典型化, I L- 8 的沉积部位下移,由表皮下层至真皮层;结论: I L- 8 是贯穿于寻常型银屑病病理的发生、发展的重要启动因素之一。
【Abstract】 OBJECTIVE:In order to know how IL-8 take continous effect to formation of dermal pathology of psoriasis; METHODS:We took fresh biopsy speimens of acute eruptive guttate psoriasis,according to duration of its appearance and made them stained with IL-8,RESULTS:IL-8 can be marked in the reratincytes in early stage of psoriasis,and moves downward to the deepth of epidermal and dermal as the dermal pathology is gradually formed.CONLUSION:IL-8 is one of important facts which set up the mechanism of psoriasis.
【基金】 黑龙江省自然科学资助
- 【文献出处】 航空航天医药 ,AEROSPACE MEDICINE , 编辑部邮箱 ,1999年03期
- 【分类号】R758.63
- 【被引频次】3
- 【下载频次】52