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X光透镜应用于蛋白大分子晶体衍射

Application of monolithic polycapillary X-ray lens in macromolecular crytallography

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【作者】 陈俊赫业军李玉德魏富忠王大椿罗萍颜一鸣

【Author】 CHEN Jun;HE Yejun; LI Yude;WEI Fuzhong;WANG DacunLUO Ping YAN Yiming(Institute of Low Energy Nuclear Physics, Beijing Normal University, Beijing 100875)

【机构】 北京师范大学低能核物理研究所!北京100875北京师范大学低能核物理研?

【摘要】 采用X光透镜替代单色仪双聚焦镜应用于生物蛋白大分子晶体衍射分析,照射晶体样品的光强提高1—2个量级,衍射强度的提高远大于5倍,大大缩短了测试时间,分辨能力改善0.02-0.06nm,信噪比也有改善。

【Abstract】 By using monolithic X-ray lens, the direct beam intensity irradiating on crystalwas 1 to 2 order of magnitude higher than the traditional method with the doublefocusing mirrors. The diffracted X-ray intensity was increased by about 5 tAnes, andthe resolution was improved by 0.02 - 0.06nm . The signal to noise ratio was alsoimproved, and the time of measurement was reduced.

【基金】 北京市自然科学基金
  • 【分类号】O434.19
  • 【被引频次】1
  • 【下载频次】63
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