【摘要】 目的 探讨6项放免指标联合诊断原发性肝癌和胃肠癌术后的复发或转移。方法 对1993年以来住院的恶性肿瘤患者130例,其中胃肠癌术后96例,原发性肝癌34例。分为稳定组和不稳定组,放免测定其血清中CA_-50,CA_-199,CEA,AFP,SF和β₂-M。结果 3项指标同时阳性,有助于原发性肝癌的诊断,亦有助于胃肠癌术后复发或转移的诊断（P<0.01）。在CA_-50,A_-199及CEA中,出现1～2项阳性者,应高度警惕胃肠癌术后复发或转移。结论 肿瘤标志物CA_-50,CA_-199,CEA、AFP、SF和β₂-M等6项,可用于联合诊断原发性肝癌和胃肠癌术后复发或转移,也可用于判断预后。更多还原

【Abstract】 Objective To explore the effect of 6 radioimmunoassay markers for the diagnosis of primary hepatic carcinoma and relapse or metastasis of gastrointestinal cancer postoperation. Metheds One hundred and thirty cases of malignant cancers hospitalized since 1993 were observed. The patients including postoperative gastrointestinal carcinoma in 96 cases and primary hepatic carcinoma in 34 cases were divided into stable group and unstable group. A series markers of CA-50, CA-199, CEA, AFP, SF and β2 - M were detected with radioimmunoassay. Results Three positive markers meantime favor to the diagnosis of primary hepatic carrinoma and relapsed or metastatic gastrointestinal cancer(P<0. 01). In the series of CA-50,CA-199 and CEA, one to two positive markers suggested the possibility of relapse or metastasis of postoperative gastrointestinal cancer . Conclusion The 6 tumor markers such as CA-50、 CA-199、CEA、AFP、SF and β2 -M can be combined to diagnose the primary hepatic carcinoma and the relaped or metastatic gastrointestinal carcinoma postoperation, and to judge their prognosis.更多还原