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硫酸腺嘌呤预处理大鼠后心肌细胞糖原的定量分析

A Quantitative Analysis of the Changes of Polysaccharides in Myocardium of the Rat with Ischemic Preconditioning by Sulphuric-Acid-Adenine

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【作者】 雷岳山; 袁玉林; 汪艳; 张友云; 冯晓祥;

【Author】 Lei Yneshan; Zhang Youyun; Wang Yan; et al(Department of Human Anatomy, Basic Medical College, Hubei Medical University, Wuhan 430071, China)

【机构】 武汉基础医学院人体解剖学教研室!武汉; 430071; 武汉基础医学院实验中心!武汉;

【摘要】 通过组化定量分析的方法,观察外源性硫酸腺嘌呤预处理及缺血再灌注的糖原稳定性的变化,探讨硫酸腺嘌呤对心肌缺血再灌注损伤的保护作用。结果显示;硫酸腺嘌呤预处理组平均光密度值与正常组差异无显著性,提示硫酸腺嘌呤显示明显的预处理效应。

【Abstract】 By IBAS image analysis system, the changes of polysaccharides in rat heart caused by traditional way and byextrinsic sulphuric-acid-adenine were quantitatively analysed in comparison wlth those in normal ischemia/reper-fusion. We aimed at observing the protective effect of extrinsic sulphuric-acid-adenine on ischemia/reperfusion in-jury to rat heart. The results showed that compared to the normal group, OPTDMs of the traditional way groupand the extrinsic sulphuric-acid-adenine group had no significant difference, and OPTDM of the ischemia/reper-fusion group reduced significantly. Therefore, the results manifested the effect of extrinsic sulphuric-acid-adenineof anti-i1ljury in myocardium caused by ischemic reperfusion.

【基金】 湖北省自然科学基金!95J31
  • 【文献出处】 湖北医科大学学报 ,Journal of Hubei Medical University , 编辑部邮箱 ,1999年04期
  • 【分类号】R96
  • 【被引频次】1
  • 【下载频次】24
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