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石棉肺患者血清TNF-α、IL-6水平的观察

Investigation of TNF- and IL-6 Levels in Asbestosis Serum

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【作者】 周建华周立人章瑜陈跃进

【Author】 Zhou Jianhua et al (Div\^of Occup\^Hlth\^,Dept\^of Prev\^Med\^,Suzhou Med\^College,Suzhou 215007 China) \=

【机构】 苏州医学院劳动卫生职业病教研室

【摘要】 采用ELISA双抗体夹心法分别检测石棉肺患者和接触石棉纤维工人血清中TNF-α和IL-6含量,探讨TNF-α和IL-6水平与石棉肺的关系。检测结果表明:石棉肺患者血清TNF-α和IL-6含量明显高于正常人和健康接尘工人(P<001)。提示石棉肺的发生与TNF-α和IL-6的异常表达有关。

【Abstract】 Concentrations of TNF- and IL-6 in serum were measured by ELISA method of double\|antibody to investigate the relationship between the levels of TNF- and IL-6 and asbestosis.The results showed that the concentrations of TNF- and IL-6 were much higher in asbestosis than those in controls( PZ]<0\^01)and healthy dust exposed workers( P <0\^01),which indicated that asbestosis was correlated with TNF- and IL-6 abnormal expression.\;

【关键词】 石棉肺TNF-αIL-6
【Key words】 Asbestosis\ TNF-\ IL-6
【基金】 江苏省卫生厅资助
  • 【文献出处】 工业卫生与职业病 ,INDUSTRIAL HEALTH AND OCCUPATIONAL DISEASES , 编辑部邮箱 ,1999年03期
  • 【分类号】R135.2
  • 【被引频次】8
  • 【下载频次】62
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