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豚鼠应激性胃溃疡模型的制作与验证的实验研究

Experiment on preparation and verification of Guinea-pig Model for Stress Gastric Ulcer

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【作者】 翁泰来张锡流叶星江赵利华

【Author】 Wong Tailal, et al (Guangxi College of TCM Nanning 530001)

【机构】 广西中医学院!南宁530001广西中医学院第一附属医院病理科!南宁

【摘要】 该实验首次应用豚鼠水浸拘束法制作应激性胃溃疡的模型,从胃溃疡指数、应激前后胃电活动的变化、胃粘膜病理改变等方面观察应激性胃溃疡的发生、发展过程。该实验模型易制作,重复性好,适合应用于应激性胃溃疡的实验研究。

【Abstract】 In the experment, guinea-pig was first used to make into a model with stress gastric ulcer by soaking guinea-pig into the water at 23±1℃ degree centigrade for 8 hours. The observation on occurring and development of stress gastric ulcer was made from the aspects of the gastric ulcer index. the changes of the gastric electric amplitude and frequency before and after shes and Pathological changes in gastric mucous membrane. The experimental model proves easy to be prepared and the method can be used repetitively for experimental study on stress gastric ulcer.

  • 【文献出处】 广西中医学院学报 ,JOURNAL OF GUANGXI COLLEGE OF T.C.M , 编辑部邮箱 ,1999年02期
  • 【分类号】R-332
  • 【被引频次】8
  • 【下载频次】254
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