【摘要】 激素、细胞因子、生长因子、粘附分子和细胞外基质均参与调节哺乳动物胚胎植入过程。在整个胚胎植入过程中，这些调节因素的表达、合成与分布状态沿着一定的空间和时间顺序发生变化，而且它们之间存在着广泛的联系。目前积累的资料显示，这些调节因素可能遵循一定的时空顺序组构成信号通路，协调胚胎和子宫两方面的变化，准确地调节胚胎植入过程。更多还原

【Abstract】 Blastocyst implantation is a strictly regulated process by hormones, growth factors, cytokines, adhesion molecules and extracellular matrix. Extensive interactions exist between the modulators and the expression and distribution of the modulat0rs change spatiallyand temporally along the progressing of blastocyst implantation. It is postulated that themodulators integrate into spatia1 and temporal signal pathways which synchronize blast0cyst and merus to enhance implantation.更多还原