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联合检测肿瘤标志物对恶性肿瘤的诊断价值
The Diagnostic Value of Combined Detection of Serum Mark for Malignant Tumor
【摘要】 目的:探讨肿瘤标志物与各种肿瘤间的关系,为肿瘤诊断提供理论依据。方法:对167例临床诊断为恶性肿瘤,22例良性肿瘤患者血清TSGF、AFP、MAO、SA4种肿瘤标志物联合检测,并与25例健康者对照。结果:良性肿瘤(组)TSGF为(60.42±17.92)U/ml,P>0.05,良性肿瘤组TSGF与健康对照组没有显著差异;恶性肿瘤各组中,TS-GF均>71u/ml,P<0.001,与健康对照组有显著差异性,其敏感性为71.86%,特异性为92%,与血清SA比较,在恶性肿瘤中,TSGF比SA较敏感,特异性高。结论:联合检测TSGF、AFP、MAO、SA能提高恶性肿瘤诊断的灵敏度。
【Abstract】 Objective: To study on the relationship between serum marks and every kind of tumor.Methods:The serum concentration of TSGF,AFP,MAO and SA wre detected in 167 cases with malignant tumor,22 cases with benign tumor and 25 cases normal control.Results:Serum levels of TSGF did not appear to be significantly different between benign tumor and normal control(P>0.05). The serum values of TSGF were obviously higher in malignant tumor group than that in benign tumor group and normal control(P<0001). The positive percentage of TSGF and SA in malignant tumor group were 7186%,92% respectively. Comparing with SA,TSGF has higher specificity and sensitivity. Conclusion:The combined detection of TSGF,AFP,MAO and SA can rise the sensitivity in diagnosis of malignant tumor.
【Key words】 tumor specific growth factor; AFP; MAO; SA; malignant tumor;
- 【文献出处】 华夏医学 ,ACTA MEDICINAE SINICA , 编辑部邮箱 ,1999年02期
- 【分类号】R730.43
- 【被引频次】2
- 【下载频次】25