【摘要】 合成了系列单链含 2 ,7-取代萘刚性生色基的双亲化合物 Cn Naph(2 ,7) C6 N+ (n=4,7,10 ,12 ,16 ) ,分别用透射电镜、 1 H NMR和 DSC观测了该系列双亲物在稀溶液中的聚集形态 ,研究了聚集体内的分子运动和凝胶态到液晶态的相变 .结果表明 ,当尾链 n≥ 7时 ,该系列化合物在稀溶液中自组织成双分子层排列的囊泡 ,当 n=4时聚集体无确定形态 .更多还原

【Abstract】 A series of single\|chain amphiphile containing 2,7\|substituted naphthalene rigid segment, alkyl tail chain and spacer portion, C\-\%n\%H\-\{\%2n\%+1\}OC\-\{10\}H\-6O（CH\-2）\-6N\++（CH\-3）\-3Br\+-（\%n\%=16, 12, 10, 7, 4）, has been synthesized. The aggregate morphology of the amphiphiles in dilute aqueous solution was observed by electron microscopy, and found to form aggregate global\|shaped vesicles with 200\₄00 nm when \%n\%≥7 and unstable dispersion when \%n\%=4. The gel to liquid crystal phase transition of the bilayer membranes was studied by means of differential scanning calorimmetry（DSC）. The molecular motion in the membranes was investigated by \{\}\+1H NMR. The experiment results indicate that the amphiphiles are of practical bilayer forming, capable of organizing biomembrane mimetic agent and suggest that the vesicle structure are composed of the bilayer structure similar to that of biomembranes. [WT5HZ]更多还原