【摘要】 目的 调查武汉地区既往职业献血员血清TTVV DNA及其他几种肝炎病毒基因的状况与特点。方法采用PCR或巢式PCR对74例既往乡村献血员进行血清TTV DNA及HCV RNA、HGV RNA的检测。结果 TTVDNA、HCV RNA及HGV RNA阳性检出率分别为43.2％、23.0％与2.7％,TTV DNA检出显著高于其他肝炎相关病毒,HCV RNA阳性率显著高于HGV RNA阳性率。结论 既往长期的献血已造成地区乡村职业献血员TTV与HCV感染率的显著升高。更多还原

【Abstract】 Objective To investigate the distribution and characteristics of TTV and other hepatitis viruses in sera of professional blood donors in Wuhan. Methods PCR or RT nested-PCR was adopted to detect TTV DNA, HCV RNA and HGV RNA in sera of 74 professional blood donors. Results TTV DNA was detected in 32(43.2% ) of the 74 blood donors, which was significantly higher than of HCV RNA(23. 0% )and HGV RNA(2. 7% )detection. Conclusion Professional blood donors has high risks for TTV transmission.更多还原