【摘要】 目的 :了解金黄色葡萄球菌医院感染的危险因素 ,以防止金黄色葡萄球菌医院感染。方法 :调查广州市三所综合性医院住院患者金黄色葡萄球菌感染的临床资料 ,按 1∶1病例—对照配比原则对危险因素进行Logistic多元回归分析。结果 :金黄色葡萄球菌医院感染中MRSA所占的比例高于社区感染。医院感染多发生于呼吸内科、神经内科、神经外科及ICU病房。常见的感染部位包括呼吸道 ,其次为手术切口、血液感染和皮肤感染 ,医院感染主要的危险因素包括使用呼吸机、感染前发生其它医院感染、使用多种抗生素、住ICU病房。结论 :合理使用抗生素 ,加强重点科室的监测 ,采取有效的消毒隔离措施是控制金黄色葡萄球菌医院感染的关键。更多还原

【Abstract】 Objective: To determine the risk factors of nosocomial infection for S. aureus in three hospital. Methods: An epidemiologgy investigation was studied. Cases were reviewed with S. aureus infection patients and logistic regression analysis was done with 1∶1 case control method. Results: The ratio of MRSA in nosocomial infection was significantly higher than that of other society infections. Respiration department, neurointemal department, neurosugery and ICU were suffered from S. aureus nosocomial infection easily. Major nosocomial infection sites included: lower respiratory tract, surgery wound, blood, skin. Major risk factors were related to nosocomial infection including:(1)respiratory machine indwelling related infections;(2) prior acquired infection;(3)treatment with various antibiotics;(4)the duration of ICU. Conclusion: Preparing use of antibiotics, making main department nosocomial surveillance, effective sterilize and separate measure were control sticking point of S aureus nosocomial infection.更多还原