【摘要】 为了解儿童因药源性疾病入院的现状,对1578例儿科住院病人进行了一次回顾性药物流行病学调查.结果表明:①有23例因药源性疾病入院,占全部儿科住院病的146%;②引起药源性疾病的药物包括解热镇痛药、抗生素、磺胺类、中药及外用药,药物种类及病例数均以解热镇痛药居首位,其次为抗生素;③临床表现的前三位依次为药疹、药物性血尿和青霉素过敏;④23例中死亡1例,病死率为4.35%;⑤解热镇痛药的非处方应用及抗生素的不合理应用是导致儿童药源性疾病入院的重要原因.更多还原

【Abstract】 An epidemiologic survey on drug-related hospital admission was carried out among 1578 pediatric inpatients. The results showed that 23 cases were admitted due to drug induced diseases, eccountiong for 1.46%. Drugs involved were analgesics, antibiotics , sulfonamides, Chinese medicinal herb and drugs for external application. The most frequently found drugs were analgesics followed by antibiotics. Manifestations in the firs three places were drug rash, drug - induced hematuria and penicillin allergy. The death rate of the cases was 4. 35%, This study suggests that the application of analgesics without prescription and unreasonable use of antibiotics were main causes for drugrelated hospital admission of children.更多还原