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地锦片和地锦注射液的制备及质量检查

The Preparation and Quality Testing of Dijin Tablets and Injection Solution

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【作者】 宋晓平李引乾张为民刘炳琪陈福星高建军

【Author】 Song Xiaoping Li Yinqian Zhang Weimin Liu Bingqi Chen Fuxing Gao Jianjun (College of Animal Science and Vetevinary Medicine Northwestern Agricultrual University,Yangling,Shaanxi 712100)

【机构】 西北农业大学动物科学与动物医学学院

【摘要】 采用地锦草水煎提取物和水醇提取物分别制备地锦片和地锦注射液并作相关质量检查,结果表明:地锦草粉、水煎浸膏、淀粉以1∶2∶2的比例所制的地锦片崩解时限为4min,10片均重3.05g,麻面率在2%以下,片子表面有小花斑;地锦草注射液的局部刺激指数<1.4级,试验兔体温升高值<0.5℃,3只体温升高总和为1.1℃,溶血试验、蛋白质和鞣质检查均为阴性。

【Abstract】 Water decoction and water ethanol extracts which were obtained from Euphorbia humifusa Wild were preparated for Dijin tablets and Dijin injection solution, and being conducted quality testing. The results showed that the crumble time of Dijin tablet was 4 min when the proportion of Dijincao powder, water decoction extract and starch was 1∶2∶2 ,and the mean weight of 10 tablets was 3 05 g. The rate of coarse face was under 2% ,but the tablet face had small colored spots.The local stimulate index of Dijin injection solution was under 1 4.The value rising temperature of every one of the rabbits was under 0 5℃, and the total value of the rising temperature of the rabbits was under 1 1℃,in addition, heamolysis test,protein and tannin testing were negative.

【关键词】 地锦草制剂制备质量检查
【Key words】 Euphorbia humifusa Wildpreparationquality testing
【基金】 西北农业大学中兽医药研究所资助项目
  • 【文献出处】 动物医学进展 ,PROGRESS IN VETERINARY MEDICINE , 编辑部邮箱 ,1999年01期
  • 【分类号】S859.79
  • 【被引频次】1
  • 【下载频次】107
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