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有机硒对地方性砷中毒体征的治疗效果及其动态的研究

THE EFFECT OF TREATMENT AND ITS DYNAMIC RESEARCH OF ENDEMIC ARSENISM PATIENTS’SIGN WITH ORGANIC SELENIUM

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【作者】 候少范; 杨林生; 李德珠; 王丽珍; 王五一; 武克恭; 夏雅娟; 李艳红; 于广军; 田素梅; 秦月鲜;

【Author】 Hou Shaofan, et alInstitute of Geography, Chinese Academy of Sciences, Beijing

【机构】 中国科学院地理研究所; 内蒙古地方病防治研究所; 内蒙古地方病防治研究所;

【摘要】 本文报道地方性砷中毒体征改变的基本特征和有机硒制剂对体征改变的临床治疗效果,结果表明,硒治疗组对体征改变的有效率为68.00%,饮用低砷水对照组25.58%,两组差异非常显著(P<0.01),显示仅切断高砷水源对体征改变的干预效果是有限的,而药物治疗是必不可缺少的措施。角化、脱色、色沉、皲裂是可定量化的实质性病变,病变和逆转过程既有独立性又互相关联,对临床诊断和探讨致病机理有理论和现实指导意义。

【Abstract】 This paper reports the basic symptoms and the clinical treating effect of endemic arsenism patients’signs changes with organic selenium preparation. The result indicates that the effective rate of patients’signs changes is 68.00% in selenium- therapy group and it is 25.58% in control group drinking low arsenic water, and difference between this two groups is significant( P < 0.01) , which shows that interfering effect to changes of patients’sign is limited only through cutting off high arsenic waterhead, but medical treatment is an essential measure. Keralinization, depigmentation, pigmentation and rhagades are pathological changes of substance which can be quantitated. There are both dependence and relevance of processes of pathological changes and reversal, which has the theoretically and realistically directive importance of clinical diagnosis and probing into mechanism of cause of ar-

  • 【文献出处】 中国地方病防治杂志 ,Chinese Journal of Control of Endemic Disease , 编辑部邮箱 ,1999年05期
  • 【分类号】R599
  • 【被引频次】7
  • 【下载频次】67
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