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不同栽培居群红花的活血化瘀作用比较

Comparison of huoxuehuayu effects of different cultivated populations of safflower

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【作者】 郭美丽张汉明张芝玉苏中武

【Author】 Guo Meili, Zhang Hanming, Zhang Zhiyu, Su Zhongwu (Department of Pharmacognosy, College of Pharmacy,Second Military Medical University,Shanghai, 200433)

【机构】 第二军医大学药学院生药学教研室

【摘要】 目的:研究不同栽培居群红花的活血化瘀作用,探讨红花的种内变异,为药材的质量评价及优良栽培居群的选育提供依据。方法:测定血小板聚集抑制率、凝血酶原时间和部分凝血活酶时间,比较不同栽培居群红花的活血化瘀作用。结果:不同栽培居群红花活血化瘀药理作用存在非常显著差异(P<0.01),对血小板聚集的抑制作用,吉木萨尔居群>简阳居群>新乡居群和巍山居群(后两者间P>0.05);对凝血酶原和部分凝血活酶时间的延长作用,巍山居群>简阳居群>新乡居群和吉木萨尔居群(后两者间P>0.05)。结论:不同居群红花的活血化瘀作用因指标不同而不同,抑制血小板聚集吉木萨尔居群最优,延长凝血时间巍山居群最优

【Abstract】 Objective: To research the huoxuehuayu effects of different cultivated populations of safflower, and probe the intraspecific variance of safflower, and provide the basis for evaluation of the crude drug and breeding of good cultivated populations. Methods: Percentage of restraining platelet aggregation, prothrombin time and partial thromboplastic time were measured to compare the huoxuehuayu effects of different populations of safflower. Results: The huoxuehuayu effects of different populations were significantly different( P <0.01). The effects on restraining platelet aggregation from strong to weak were Jimusa′er population, Jianyang population, Xinxiang population and Weishan population ( P >0.05 between the last two populations).The effects on prolonging prothrombin time and partial thromboplastic time from long to short were Weishan population, Jianyang population, Xinxiang population and Jimusa′er population( P >0.05 between the last two populations). Conclusion: The huoxuehuayu effects of different cultivated populations of safflower were different because of the different indexes. Jimusa′er population was best on restraining platelet aggregation. Weishan population was best on prolonging prothrombin time and partial thromboplastic time.

【基金】 国家自然科学基金
  • 【文献出处】 第二军医大学学报 ,ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY , 编辑部邮箱 ,1999年01期
  • 【分类号】R282.703
  • 【被引频次】14
  • 【下载频次】129
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