【摘要】 目的观察高血压伴或不伴缺血性脑卒中患者的纤溶系统的变化。方法观察了47例高血压伴缺血性脑卒中患者和20例无缺血性脑卒中的高血压患者纤溶系统的变化，并与24例健康对照组进行了比较。结果高血压伴缺血性脑卒中患者t－PA和纤溶酶原明显低于单纯高血压组（P＜0．05）和健康对照组（P＜0．01）；而PAI和D一二聚体及纤维蛋白原明显高于高血压病患者（P＜0．05）和健康对照组（P＜0．01）；单纯高血压病患者t－PA和纤溶酶原明显低于健康对照组（P＜0．05），而PAI和D－二聚体及纤维蛋白原明显高于健康对照组（P＜0．05）。结论高血压病患者存在有血纤溶功能异常，尤以高血压伴缺血性脑卒中患者更为明显。血栓形成和血纤溶功能异常可能在急性缺血性脑血管病发病过程中起着重要的作用。更多还原

【Abstract】 Observed the alteration of fibrinolytic system in hypertensiv patients with ischemic stroke and twenty cases of hypertensive patients. Results t-PA and plasminog-en (PLg) were significantly lower in hypertensive patients with ischemic stroke than in hypertension group and healthy control group, but PAI and D-D and fibrinogen(FbG) were significantly higher in hypertensive patients with ischemic stroke than in hypertension group and healthy control group. Thet t-PA and PLg were significantly lower in hypertension group than in healthy control group, but PAI and D-D and FbG were significantly higher in hypertension group than in healthy control group. Conclusion There were abnormal fibrinolytic activities in patients with hypertension, especially in hypertensive patments with ischmic stroke.更多还原