【摘要】 报道了一种分析普鲁卡因的新型离子敏感场效应晶体管传感器。研究了以ＤＭ－β－ＣＤ、Ｎａ－ＴＰＢ为电活性物质时传感器的性能。以Ｎａ－ＴＰＢ为活性物质时，传感器对普鲁卡因的Ｎｅｒｎｓｔ响应范围为（１．０×１０－１～１．５×１０－５）ｍｏｌ／Ｌ，适宜ｐＨ范围为３．０～７．５，响应灵敏度为５７．５ｍＶ／ｐＣ，检出极限为８．５×１０－６ｍｏｌ／Ｌ。用其分析普鲁卡因注射液含量，结果和药典方法吻合。更多还原

【Abstract】 The new procaine ISFET reported in this paper is a PVC matrix made from dimethyl-β-cyclodextrin or NaTPB (Sodium tetraphenylboron) as electric active materials. The sensor has Nernst response for procaine with a slope of 57 5 mV/decade over the concertration ranges of (1 0×10 -1 ～1 5×10 -5 )mol/L at pH 3 0～7 5. The determination limt is 8 5×10 -6 mol/L. It is used for determination of procaine in injection, the results agree with the method in Pharmacopoeia of China .更多还原